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[4] The interaction between Epithalon and the SIRT1/SIRT6 sirtuin-mediated chromatin deacetylation pathway which plays a documented role in telomere maintenance and DNA repair warrants investigation given the mechanistic overlap at the chromatin level

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89 In addition, SIRT1 mediates multi-target protection against oxidative stress, coordinates autophagy and ER stress responses, and regulates immuneinflammatory activity

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